KMS Nanjing Institute of Geology and Palaeonotology,CAS
| Molecular evidence of keratin and melanosomes in feathers of the Early Cretaceous bird Eoconfuciusornis | |
Pan, Yanhong1 ; Zheng, Wenxia2; Moyer, Alison E.2,7; O'Connor, Jingmai K.3; Wang, Min3; Zheng, Xiaoting4,5; Wang, Xiaoli4; Schroeter, Elena R.2; Zhou, Zhonghe3; Schweitzer, Mary H.2,6
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| 2016-12-06 | |
| Source Publication | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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| ISSN | 0027-8424 |
| Volume | 113Issue:49Pages:E7900-E7907 |
| Abstract | Microbodies associated with feathers of both nonavian dinosaurs and early birds were first identified as bacteria but have been reinterpreted as melanosomes. Whereas melanosomes in modern feathers are always surrounded by and embedded in keratin, melanosomes embedded in keratin in fossils has not been demonstrated. Here we provide multiple independent molecular analyses of both microbodies and the associated matrix recovered from feathers of a new specimen of the basal bird Eoconfuciusornis from the Early Cretaceous Jehol Biota of China. Our work represents the oldest ultrastructural and immunological recognition of avian beta-keratin from an Early Cretaceous (similar to 130-Ma) bird. We apply immunogold to identify protein epitopes at high resolution, by localizing antibody-antigen complexes to specific fossil ultrastructures. Retention of original keratinous proteins in the matrix surrounding electron-opaque microbodies supports their assignment as melanosomes and adds to the criteria employable to distinguish melanosomes frommicrobial bodies. Our work sheds new light on molecular preservation within normally labile tissues preserved in fossils. |
| Keyword | keratinous protein immunogold ChemiSTEM melanosome Early Cretaceous |
| DOI | 10.1073/pnas.1617168113 |
| Language | 英语 |
| WOS Keyword | BETA BETA KERATINS ; EUMELANIN PIGMENT ; FOSSIL FEATHERS ; EVOLUTION ; COLOR ; THEROPOD ; DINOSAUR ; PLUMAGE ; CHINA ; PRESERVATION |
| Funding Project | State of North Carolina ; National Science Foundation[ECCS-1542015] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB18030501] ; National Natural Science Foundation of China[41472009] ; National Natural Science Foundation of China[91514302] ; Open-Lab Grants of the LPS ; National Science Foundation USA (INSPIRE Program)[EAR-1344198] ; National Science Foundation USA (INSPIRE Program)[DGE01252376] ; David and Lucile Packard Foundation |
| WOS Research Area | Science & Technology - Other Topics |
| WOS Subject | Multidisciplinary Sciences |
| WOS ID | WOS:000389536700004 |
| Funding Organization | State of North Carolina ; National Science Foundation ; Strategic Priority Research Program of the Chinese Academy of Sciences ; National Natural Science Foundation of China ; Open-Lab Grants of the LPS ; National Science Foundation USA (INSPIRE Program) ; David and Lucile Packard Foundation |
| Publisher | NATL ACAD SCIENCES |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.nigpas.ac.cn/handle/332004/12773 |
| Collection | 部分文献的图版及图版说明 |
| Corresponding Author | Pan, Yanhong; Zhou, Zhonghe; Schweitzer, Mary H. |
| Affiliation | 1.Chinese Acad Sci, Nanjing Inst Geol & Palaeontol, Key Lab Econ Stratig & Palaeogeog, Nanjing 210008, Jiangsu, Peoples R China 2.North Carolina State Univ, Dept Biol Sci, Raleigh, NC 27695 USA 3.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Key Lab Vertebrate Evolut & Human Origins, Beijing 100044, Peoples R China 4.Linyi Univ, Inst Geol & Paleontol, Linyi 276005, Shandong, Peoples R China 5.Shandong Tianyu Museum Nat, Pingyi 273300, Shandong, Peoples R China 6.North Carolina Museum Nat Sci, Raleigh, NC 27601 USA 7.Drexel Univ, Dept Biol, Philadelphia, PA 19104 USA |
| Recommended Citation GB/T 7714 | Pan, Yanhong,Zheng, Wenxia,Moyer, Alison E.,et al. Molecular evidence of keratin and melanosomes in feathers of the Early Cretaceous bird Eoconfuciusornis[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2016,113(49):E7900-E7907. |
| APA | Pan, Yanhong.,Zheng, Wenxia.,Moyer, Alison E..,O'Connor, Jingmai K..,Wang, Min.,...&Schweitzer, Mary H..(2016).Molecular evidence of keratin and melanosomes in feathers of the Early Cretaceous bird Eoconfuciusornis.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,113(49),E7900-E7907. |
| MLA | Pan, Yanhong,et al."Molecular evidence of keratin and melanosomes in feathers of the Early Cretaceous bird Eoconfuciusornis".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113.49(2016):E7900-E7907. |
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| File Name/Size | DocType | Version | Access | License | ||
| Molecular evidence o（2167KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | Application Full Text | |
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